Nova studija.JAMA Internal Medicine: Use of Antihypertensive Medications and Breast Cancer Risk
AmongWomen Aged 55 to 74 Years
Christopher I. Li, MD, PhD; Janet R. Daling, PhD; Mei-Tzu C. Tang, PhD; Kara L. Haugen, MS;
Peggy L. Porter, MD; Kathleen E. Malone, PhD
Rezultati-
„Current use of calcium-channel blockers for 10 or more years was associated with
higher risks of ductal breast cancer (odds ratio [OR], 2.4; 95%CI, 1.2-4.9) (P = .04 for trend)
and lobular breast cancer (OR, 2.6; 95%CI, 1.3-5.3) (P = .01 for trend). This relationship did
not vary appreciably by type of calcium-channel blocker used (short-acting vs long-acting,
dihydropyridines vs non-dihydropyridines). In contrast, use of diuretics, β-blockers, and
angiotensin II antagonists were not associated with risk.”

U prevodu koriscenje lekova kalcijum-blokera 10 i vise godina je povezano sa većim rizikom od raka dojke (ductal i lobular). Ovaj odnos nije zavisio od vrste leka (kratko ili dugo-dejstvujuci). Ostali lekovi kao diuretici, beta-blokeri i angiotensin antagonisti nisu povezani sa ovim rizikom.